Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review case 348 what's black hairy tongue? lingua villosa Nigra, tetracycline, melanosis, leucoplakia ,navi Pigmented fungiform papillae, or papillary tip melanosis Registered Dental Hygienists ORAL MELANOSIS leading to the diagnosis of HIV infection. Despite being a weak association, any unexplained oral pigmentation in a high risk individual should make one suspect HIV associated oral melanosis and proceed Cancer patient's tongue turned black and hairy 'after rare antibiotics reaction' The Independent Oral Mucosal Melanosis IntechOpen